GJA8 Rabbit Polyclonal Antibody

CAT#: TA350758

Rabbit Polyclonal Anti-GJA8 Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA350758 (GJA8 Antibody) at dilution 1/15 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA350758 (GJA8 Antibody) at dilution 1/15, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA350758 (GJA8 Antibody) at dilution 1/15 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA350758 (GJA8 Antibody) at dilution 1/15, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human GJA8
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: gap junction protein alpha 8
• Database Link:
  NP_005258
  Entrez Gene 14616 MouseEntrez Gene 29601 RatEntrez Gene 2703 Human
  UniProt ID P48165
• Background: This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome.
• Synonyms: CAE; CAE1; CTRCT1; CX50; CZP1; MP70

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Other, Transmembrane