ICOS Ligand (ICOSLG) Rabbit Polyclonal Antibody

CAT#: TA350632

Rabbit Polyclonal Anti-ICOSLG Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 80 μg Lane 1-2: Human fetal brain tissue human lymphoma tissue Primary antibody: TA350632 (ICOSLG Antibody) at dilution 1/100 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 minutes

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human fetal brain and human lymphoma tissue
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human ICOSLG
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 33 kDa
• Gene Name: inducible T-cell costimulator ligand
• Database Link:
  NP_056074
  Entrez Gene 23308 Human
  UniProt ID O75144
• Background: ICOS ligand is a protein that in humans is encoded by the ICOSLG gene. ICOSLG has also been designated as CD275 (cluster of differentiation 275). Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
• Synonyms: B7-H2; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; LICOS

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)