CD18 (ITGB2) Rabbit Polyclonal Antibody

CAT#: TA350097

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Rabbit Polyclonal Anti-ITGB2 Antibody


 Product Datasheet for 'TA350097'

USD 345.00


Availability*
In Stock

Size
    • 100 ul


Product images

Specifications

Product Data
Applications IHC, WB
Recommend Dilution ELISA: 2000-5000, WB: 500-2000, IHC: 25-100
Reactivity Human, Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human ITGB2
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration 2.5 mg/ml
Purification Antigen affinity purification
Predicted Protein Size 85 kDa
Gene Name integrin subunit beta 2
Background The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.
Synonyms CD18; LAD; LCAMB; LFA-1; MAC-1; MF17; MFI7
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity, Regulation of actin cytoskeleton, Viral myocarditis
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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