Myosin Phosphatase (PPP1R12A) Rabbit Polyclonal Antibody

CAT#: TA348924

Rabbit Polyclonal Anti-Phospho-MYPT1 (Thr853) Antibody

Product Images

Western blot analysis of MYPT1 (Phospho-Thr853) expression in NIH/3T3 cell extract

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Phospho-MYPT1 (Thr853) Antibody: The antiserum was produced against synthesized peptide derived from human MYPT1 around the phosphorylation site of Thr853.
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 115 kDa
• Gene Name: protein phosphatase 1 regulatory subunit 12A
• Database Link:
  NP_002471
  Entrez Gene 17931 MouseEntrez Gene 116670 RatEntrez Gene 4659 Human
  UniProt ID O14974
• Background: Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.
• Synonyms: M130; MBS; MYPT1
• Note: MYPT1 (Phospho-Thr853) Antibody detects endogenous levels of MYPT1 only when phosphorylated at threonine853.

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Focal adhesion, Long-term potentiation, Regulation of actin cytoskeleton, Vascular smooth muscle contraction