Ku70 (XRCC6) Rabbit Polyclonal Antibody

CAT#: TA348033

Rabbit Polyclonal Anti-Ku70/80 Antibody


USD 380.00

4 Weeks*

Size
    • 100 ug

Product Images

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Recombinant protein of human X-ray repair complementing defective repair in Chinese hamster cells 6 (XRCC6), 20 µg
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Specifications

Product Data
Applications WB
Recommended Dilution WB: 1:500-1:2000
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen The immunogen for anti-Ku70/80 Antibody: A synthesized peptide derived from human Ku70/80
Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
Concentration lot specific
Purification Immunogen affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 70, 82 kDa
Gene Name X-ray repair complementing defective repair in Chinese hamster cells 6
Background The Ku autoantigen is a heterodimer of 70kDa (p70) and 80kDa (p80) proteins. The p70 / p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. The Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
Synonyms CTC75; CTCBF; G22P1; KU70; ML8; TLAA
Note Ku70/80 Antibody detects endogenous levels of total Ku70/80
Reference Data
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Non-homologous end-joining

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.