Leptin (LEP) Mouse Monoclonal Antibody [Clone ID: 7E3-D11-B7]

CAT#: TA346995

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Mouse Monoclonal Leptin Antibody



USD 380.00


Availability*
4 Weeks

Size
    • 100 ul


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Specifications

Product Data
Clone Name 7E3-D11-B7
Applications ELISA
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen The immunogen for LEP antibody: purified recombinant full length of human Leptin protein expressed in E.coli.
Formulation Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Purification Affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name leptin
Background This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.
Synonyms LEPD; OB; OBS
Reference Data
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Adipocytokine signaling pathway, Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Neuroactive ligand-receptor interaction
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.