GADD45A Mouse Monoclonal Antibody [Clone ID: 6C3-G3-E9]

CAT#: TA346952

Mouse Monoclonal GADD45a Antibody

Specifications

Product Data

• Clone Name: 6C3-G3-E9
• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: The immunogen for GADD45A antibody: purified recombinant human GADD45 a protein expressed in E.coli
• Formulation: Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 22 kDa
• Gene Name: growth arrest and DNA damage inducible alpha
• Database Link:
  NP_001915
  Entrez Gene 1647 Human
  UniProt ID P24522
• Background: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.(provided by RefSeq, Dec 2010).
• Synonyms: DDIT1; GADD45

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Cell cycle, MAPK signaling pathway, p53 signaling pathway