DDX3 (DDX3X) Mouse Monoclonal Antibody [Clone ID: 6G8-F4-E3]

CAT#: TA346931

Mouse Monoclonal DDX3 Antibody

Specifications

Product Data

• Clone Name: 6G8-F4-E3
• Applications: IF, IP, WB
• Recommended Dilution: WB: 1:1000, IF: 1:200
• Reactivities: Human, Monkey, Rat, Mouse
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: The immunogen for DDX3X antibody: purified recombinant human DDX3 protein fragments expressed in E.coli.
• Formulation: Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide,0.1mg/mlBSA and 50% glycerol.
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 75 kDa
• Gene Name: DEAD-box helicase 3, X-linked
• Database Link:
  NP_001347
  Entrez Gene 13205 MouseEntrez Gene 317335 RatEntrez Gene 1654 Human
  UniProt ID O00571
• Background: DEAD box proteins,characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD),are putative RNA helicases.They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation,nuclear and mitochondrial splicing,and ribosome and spliceosome assembly.Based on their distribution patterns,some members of this family are believed to be involved in embryogenesis,spermatogenesis,and cellular growth and division.This gene encodes a DEAD box protein,which interacts specifically with hepatitis C virus core protein resulting a change in intracellular location.This gene has a homolog located in the nonrecombining region of the Y chromosome.The protein sequence is 91% identical between this gene and the Y-linked homolog.Alternative splicing results in multiple transcript variants. [provided by RefSeq,Jul 2010]
• Synonyms: CAP-Rf; DBX; DDX3; DDX14; HLP2

Reference Data

• Protein Families: ES Cell Differentiation/IPS
• Protein Pathways: RIG-I-like receptor signaling pathway