Aurora A (AURKA) Mouse Monoclonal Antibody [Clone ID: 1F8]
CAT#: TA336917
Mouse Monoclonal Aurora A Antibody (1F8)
USD 436.00
USD 200.00
USD 867.00
Specifications
Product Data | |
Clone Name | 1F8 |
Applications | ELISA, FC, ICC/IF, WB |
Recommended Dilution | Flow Cytometry: 1:200-1:400, ELISA: 1:10000, Western Blot: 1:500-1:2000, Immunocytochemistry/ Immunofluorescence: 1:200-1:1000 |
Reactivities | Human, Rat, Primate |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of human Aurora A expressed in E. coli. [UniProt# O14965] |
Formulation | PBS, 0.03% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Concentration | lot specific |
Purification | Ammonium sulfate precipitation |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 48 kDa |
Gene Name | aurora kinase A |
Database Link | |
Background | Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines. |
Synonyms | AIK; ARK1; AURA; BTAK; PPP1R47; STK6; STK7; STK15 |
Note | This Aurora A (1F8) antibody is useful for Western blot, Immunocytochemistry/Immunofluorescence, Flow Cytometry and ELISA. |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase, Stem cell - Pluripotency |
Protein Pathways | Oocyte meiosis |
Documents
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