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TLR1 Rabbit Polyclonal Antibody

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SKU
TA336407
Rabbit Polyclonal TLR1 Antibody
Size:
100 ug
Conjugation:
Unconjugated
  $610.00
5 Days*
Bulk/Customize

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Specifications
Specifications
Product Data
Application Dot, FC, IHC, WB
Recommended Dilution Flow Cytometry: 2-4 ug/ 1x10-6 cells, Western Blot: 1-3 ug/ml, Immunohistochemistry-Paraffin: 10 ug/ml, Flow (Cell Surface), Flow (Intracellular): 0.5-1 ug/1 million cells, Immunohistochemistry, Dot Blot
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Clonality Polyclonal
Immunogen This antibody was developed against a KLH-conjugated synthetic peptide corresponding to a sequence within amino acids 400-450 of human TLR1.
Buffer PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration lot specific
Purification Protein G purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name toll like receptor 1
Database Link
Background The Toll-like receptor (TLR) family in mammals are comprised of a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and an IL-1 receptor motif in the cytoplasmic domain. The TLRs could constitute an important and unrecognized component of innate immunity in humans. In mice, TLR1 interacts with TLR2 and coexpression of TLR1 and TLR2 enhance the NF-kappaB activation in response to a synthetic lipopeptide. They recognize the lipid configuration of the native mycobacterial lipoprotein as well as several triacylated lipopeptides.
Synonyms CD281; rsc786; TIL; TIL. LPRS5
Note Flow (Cell Surface): 0.5-1 ug/10^6 cells, or see Wong et al, 2007 Flow (Intracellular): 0.5-1 ug/10^6 cells
Reference Data
Protein Categories CD Markers, Cytokines, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, Transmembrane
Protein Pathways Toll-like receptor signaling pathway
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.