JNK1 (MAPK8) Rabbit Polyclonal Antibody

CAT#: TA336276

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Rabbit Polyclonal JNK1 Antibody



USD 410.00


Availability*
5 Days

Size
    • 100 ul


Product images

Specifications

Product Data
Applications WB
Recommended Dilution WB: 1:2000, ELISA: 1:100-1:2000, IHC: 1:200-1:500, IHC-P: 1:200-1:500
Reactivity C. elegans (Does not react with: Human, Mammalian, Mouse, Rat)
Host Rabbit
Clonality Polyclonal
Immunogen A recombinant protein made to the C-terminus (residues 228-451) of the C. elegans JNK1 alpha protein.
Formulation Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Concentration lot specific
Purification Whole antisera
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name mitogen-activated protein kinase 8
Background The insulin signaling pathway plays a pivotal role in lifespan regulation and stress resistance in many diverse organisms. Components of the JNK (c-Jun N-terminal kinase) signaling pathway have been shown to interact with the insulin signaling pathway. The JNK family is a subgroup of the mitogen-activated protein kinase superfamily and is part of a signal transduction cascade that is activated by cytokines and by exposure to environmental stresses. Thus, JNK1 plays a role in regulating both life span and stress resistance.
Synonyms JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c
Note This JNK1 antibody is useful for ELISA, Immunohistochemistry-Paraffin and Western blot where a band can be seen at ~53kDa (alpha form) and at ~42kDa (beta form).
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase
Protein Pathways Adipocytokine signaling pathway, Colorectal cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Fc epsilon RI signaling pathway, Focal adhesion, GnRH signaling pathway, Insulin signaling pathway, MAPK signaling pathway, Neurotrophin signaling pathway, NOD-like receptor signaling pathway, Pancreatic cancer, Pathways in cancer, Progesterone-mediated oocyte maturation, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, Wnt signaling pathway
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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