HGF Rabbit Polyclonal Antibody

CAT#: TA335252

Rabbit Polyclonal Anti-HGF Antibody

Antibody Service

 Product Datasheet for 'TA335252'

USD 360.00

5 Days

    • 50 ug

Product images


Product Data
Applications WB
Recommend Dilution WB
Reactivity Human, Rabbit, Bovine, Pig, Horse, Rat, Mouse, Dog
Host Rabbit
Clonality Polyclonal
Immunogen The immunogen for anti-HGF antibody: synthetic peptide directed towards the middle region of human HGF. Synthetic peptide located within the following region: NENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVI
Isotype IgG
Formulation Shipped as lyophilized powder. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purification Affinity Purified
Predicted Protein Size 83 kDa
Gene Name hepatocyte growth factor
Background Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity.
Note Immunogen Sequence Homology: Dog: 100%; Pig: 100%; Rat: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Bovine: 100%; Rabbit: 100%; Guinea pig: 93%
Reference Data
Protein Families ES Cell Differentiation/IPS, Transmembrane, Protease, Adult stem cells, Druggable Genome
Protein Pathways Cytokine-cytokine receptor interaction, Focal adhesion, Pathways in cancer, Renal cell carcinoma, Melanoma
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.