Heparin Cofactor II (SERPIND1) Rabbit Polyclonal Antibody

CAT#: TA332957

Rabbit anti-SERPIND1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using SERPIND1 antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human SERPIND1
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 499
• Gene Name: serpin family D member 1
• Database Link:
  NP_000176
  Entrez Gene 15160 MouseEntrez Gene 3053 Human
  UniProt ID P05546
• Background: The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency.
• Synonyms: D22S673; HC2; HCF2; HCII; HLS2; LS2; THPH10

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Complement and coagulation cascades