Estrogen Receptor beta(ESR2) Rabbit Polyclonal Antibody

CAT#: TA332550

Rabbit anti-ESR2 Polyclonal Antibody


 Product Datasheet for 'TA332550'

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USD 335.00


Availability*
3 Weeks

Size
    • 100 ug

Product images

Specifications

Product Data
Applications WB
Recommend Dilution WB 1:500 - 1:2000, IHC 1:50- 1:200
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant protein of human ESR2
Isotype IgG
Formulation Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration 1mg/ml
Purification Affinity purification
Gene Name estrogen receptor 2
Background This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.
Synonyms ER-BETA|ESR-BETA|ESRB|ESTRB|Erb|NR3A2
Reference Data
Protein Families Nuclear Hormone Receptor, Transcription Factors, Druggable Genome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.