COX15 Mouse Monoclonal Antibody [Clone ID: 7H8.2C12]

CAT#: TA328076

Mouse Monoclonal anti-Cytochrome c Antibody

Product Images

Hela cell extract was resolved by electrophoresis, transferred to nitrocellulose, and probed with anti-cytochrome C (clone 7H8.2C12) antibody. Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and a chemiluminescence detection system.

Specifications

Product Data

• Clone Name: 7H8.2C12
• Applications: WB
• Recommended Dilution: WB
• Reactivities: Broad
• Host: Mouse
• Isotype: IgG2a, kappa
• Clonality: Monoclonal
• Immunogen: Horse cyt c-OVA
• Formulation: This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
• Purification: The antibody was purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 15 kD
• Gene Name: COX15 cytochrome c oxidase assembly homolog
• Database Link:
  NP_004367
  Entrez Gene 1355 Human
  UniProt ID Q7KZN9
• Background: Cytochrome c is a 15 kD protein found in the mitochondrial intermembrane space with a heme-binding domain. Cytochrome c is a component of the electron transport chain; the heme group transfers electrons from cytochrome b-c1 complex to cytochrome oxidase complex. Cytochrome c initiates apoptosis by release to cytoplasm and binding Apaf-1 which activates procaspase 9. Cytochrome c interacts with the cytochrome b-c1 complex, cytochrome oxidase complex, heme, Apaf-1, and Caspase 9 proteins. The 7H8.2C12 monoclonal antibody recognizes cytochrome-c from most species and has been shown to be useful for Western blotting.
• Synonyms: CEMCOX2

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Metabolic pathways, Oxidative phosphorylation, Porphyrin and chlorophyll metabolism