CD46 Rat Monoclonal Antibody [Clone ID: TUG8]

CAT#: TA328055

Rat Monoclonal anti-mMCP-8 Antibody


USD 467.00

5 Days*

Size
    • 100 ug

Product Images

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Specifications

Product Data
Clone Name TUG8
Applications WB
Recommended Dilution WB
Reactivities Mouse
Host Rat
Isotype IgG2a
Clonality Monoclonal
Immunogen Recombinant GST-mouse mMCP-8 fusion protein expressed in E.coli
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Concentration lot specific
Purification The antibody was purified by affinity chromatography.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name CD46 molecule
Background mMCP-8 and its rat homologues, rMCP-8, -9, and -10, form a new group of mast cell/basophil proteases, which are more closely related to the T-cell granzymes and neutrophil cathepsin G than to the mast cell tryptases and chymases. mMCP-8 showed a high degree of homology with mouse granzyme B in the critical regions for determining substrate cleavage specificity. It preferentially cleaves after Asp residues. mMCP-8 mRNA is highly expressed in a mouse connective tissue MC-like tumor line. However, it could not be detected in mouse liver, intestine, lung or ears, indicating very low expression in normal tissues. A strong increase in mMCP-8 levels in the lungs can be detected in infected animals.
Synonyms AHUS2; MCP; MIC10; TLX; TRA2.10
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Complement and coagulation cascades

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.