PLCG 2 (PLCG2) Rabbit Polyclonal Antibody

CAT#: TA327911

Rabbit Polyclonal Phospho-PLCG2 (Tyr753) Antibody (Phospho-specific)

Product Images

Western blot analysis of PLCG2 phosphorylation expression in HepG2 whole cell lysates, The lane on the left is treated with the antigen-specific peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000, IHC: 1:50-1:200
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human PLCG2 around the phosphorylation site of Tyrosine 753.
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 150 kDa
• Gene Name: phospholipase C gamma 2
• Database Link:
  NP_002652
  Entrez Gene 29337 RatEntrez Gene 234779 MouseEntrez Gene 5336 Human
  UniProt ID P16885
• Background: Enzymes of the phospholipase C family catalyze the hydrolysis of phospholipids to yield diacylglycerols and water-soluble phosphorylated derivatives of the lipid head groups. A number of these enzymes have specificity for phosphoinositides.
• Synonyms: APLAID; FCAS3; PLC-gamma-2; PLC-IV
• Note: Phospho-PLCG2 (Tyr753) Antibody detects endogenous levels of PLCG2 only when phosphorylated at Tyrosine 753.

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: B cell receptor signaling pathway, Calcium signaling pathway, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Glioma, Inositol phosphate metabolism, Leukocyte transendothelial migration, Metabolic pathways, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pathways in cancer, Phosphatidylinositol signaling system, VEGF signaling pathway, Vibrio cholerae infection