E Cadherin (CDH1) Rabbit Monoclonal Antibody [Clone ID: EP700Y]
USD 665.00
USD 200.00
USD 867.00
Specifications
Product Data | |
Clone Name | EP700Y |
Applications | IHC |
Recommended Dilution | IHC: 1:50 - 1:200 |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Monoclonal |
Formulation | This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | cadherin 1 |
Database Link | |
Synonyms | Arc-1; CD324; CDHE; ECAD; LCAM; UVO |
Note | E-cadherin is an adhesion protein that is expressed in cells of epithelial lineage. Anti-E-cadherin stains positively in glandular epithelium as well as adenocarcinomas of the lung, G.I. tract, and ovary. Another application involves the differentiation of ductal (which stains positive) vs. lobular cancer of the breast. It has also been shown to be positive in some thyroid carcinomas. Loss of E-cadherin expression has been suggested as a poor prognostic sign in breast carcinoma and non-small cell lung carcinoma. |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
Protein Pathways | Adherens junction, Bladder cancer, Cell adhesion molecules (CAMs), Endometrial cancer, Melanoma, Pathogenic Escherichia coli infection, Pathways in cancer, Thyroid cancer |
Documents
Product Manuals |
FAQs |
SDS |
{0} Product Review(s)
Be the first one to submit a review