Shank1 Mouse Monoclonal Antibody [Clone ID: S22-21]

CAT#: TA326582

Mouse Monoclonal Anti-SHANK1 Antibody

Product Images

Western blot analysis of Shank1 in rat brain membrane lysates using a 1:1000 dilution of the antibody

Specifications

Product Data

• Clone Name: S22-21
• Applications: WB
• Recommended Dilution: WB: 1-10ug/ml, IHC: 0.1-1.0ug/ml, IF: 1.0-10ug/ml
• Reactivities: Mouse, Human, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Fusion protein amino acids 469-691 (SH3/PDZ domains) of rat Shank1
• Formulation: PBS pH7.4, 50% glycerol
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: SH3 and multiple ankyrin repeat domains 1
• Database Link:
  NP_113939
  Entrez Gene 50944 HumanEntrez Gene 243961 MouseEntrez Gene 78957 Rat
  UniProt ID Q9WV48
• Background: Shank proteins make up a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins . Shank1 specifically might be relevant to human autism spectrum disorders, due to its differential role in specific cognitive processes, along with its importance for synapse structure and function in vivo .
• Synonyms: SPANK-1; SSTRIP; synamon
• Note: Detects ~190-220 kDa (alternative splice variants). No cross-reactivity against Shank2 or Shank3.