Caspr2 (CNTNAP2) Mouse Monoclonal Antibody [Clone ID: S67-25]

CAT#: TA326393

Mouse monoclonal CASPR2 Antibody


USD 530.00

2 Weeks*

Size
    • 100 ug

Product Images

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Specifications

Product Data
Clone Name S67-25
Applications IHC, WB
Recommended Dilution WB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Fusion protein 96-1265 (extracellular domain) of human CASPR2
Formulation PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration lot specific
Purification Protein G Purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name contactin associated protein-like 2
Background Caspr (contactin-associated protein) is a part of the neurexin family. It lies in the paranodal section of the myelin sheath. Its role is for myelin sheath attachment along with contactin in a cis-complex . Caspr and Caspr2 regulate the formation of distinct axonal domains around the nodes of Ranvier. Caspr is required for the generation of a membrane barrier at the paranodal junction, whereas Caspr serves as a membrane scaffold that clusters Kv1 channels at the juxtaparanodal region. Both interact with protein 4.1B .
Synonyms AUTS15; CASPR2; CDFE; NRXN4; PTHSL1
Note Detects ~180kDa. No cross reactivity to CASPR/Paranodin
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs)

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.