RUNX1 Rabbit Polyclonal Antibody

CAT#: TA325833

Rabbit Polyclonal AML1 (Ser276) Antibody (Phospho-specific)

Product Images

Western blot analysis of AML1 phosphorylation expression in Jurkat whole cell lysates, The lane on the left is treated with the antigen-specific peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human AML1 around the phosphorylation site of Serine 276
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 50 kDa
• Gene Name: runt related transcription factor 1
• Database Link:
  NP_001001890
  Entrez Gene 12394 MouseEntrez Gene 50662 RatEntrez Gene 861 Human
  UniProt ID Q01196
• Background: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters.
• Synonyms: AML1; AML1-EVI-1; AMLCR1; CBFA2; EVI-1; PEBP2aB

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors
• Protein Pathways: Acute myeloid leukemia, Chronic myeloid leukemia, Pathways in cancer