DUSP1 Rabbit Polyclonal Antibody

CAT#: TA325421

Rabbit Polyclonal MKP-1/2 (Ser296/318) Antibody (Phospho-specific)

Product Images

Western blot analysis of MKP-1/2 phosphorylation expression in heatshockK562 whole cell lysates, The lane on the left is treated with the antigen-specific peptide.

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  Figure from citation: Western blot analysis of DUSP1 protein level by using anti-DUSP1 antibody in monocytes isolated by negative magnetic bead sorting from young (n = 6) and older (n = 6) subjects at baseline. View Citation

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human MKP-1/2 around the phosphorylation site of Serine 296/318
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 45 kDa
• Gene Name: dual specificity phosphatase 1
• Database Link:
  NP_004408
  Entrez Gene 19252 MouseEntrez Gene 114856 RatEntrez Gene 1843 Human
  UniProt ID P28562
• Background: The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus.
• Synonyms: CL100; HVH1; MKP-1; MKP1; PTPN10

Reference Data

• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: MAPK signaling pathway