p38 (CRK) Rabbit Polyclonal Antibody

SKU TA325391

Rabbit Polyclonal CrkII (Tyr221) Antibody (Phospho-specific)

Product Data

• Application: WB
• Recommended Dilution: WB: 1:500-1:2000; IF/ICC: 1:100-1:500
• Reactivity: Human, Mouse, Rat
• Modification: Phospho-specific
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human CrkII around the phosphorylation site of Tyrosine 221
• Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 42 kDa
• Gene Name: v-crk avian sarcoma virus CT10 oncogene homolog
• Database Link:
  NP_005197
  P46108
• Background: Crk an adaptor protein with an SH2-SH3-SH3 domain structure. Recruits cytoplasmic proteins through SH2-phospho-tyrosine interaction. Phosphorylated by Abl, IGF-IR and EGFR.
• Synonyms: CRKII; p38

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Chemokine signaling pathway, Chronic myeloid leukemia, ErbB signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Insulin signaling pathway, MAPK signaling pathway, Neurotrophin signaling pathway, Pathways in cancer, Regulation of actin cytoskeleton, Renal cell carcinoma