CNTF Receptor alpha(CNTFR) Rabbit Polyclonal Antibody

CAT#: TA324163

Anti-CNTFR Rabbit Polyclonal Antibody


 Product Datasheet for 'TA324163'

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USD 335.00


Availability*
3 Weeks

Size
    • 100 ul

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Specifications

Product Data
Applications WB, IHC
Recommend Dilution ELISA: 1:1000-5000, WB: 1:500-2000, IHC: 1:25-100
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Fusion protein corresponding to a region derived from 23-342 amino acids of human ciliary neurotrophic factor receptor
Isotype IgG
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration 0.6mg/ml
Purification Antigen affinity purification
Predicted Protein Size 41kDa
Gene Name ciliary neurotrophic factor receptor
Background This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor; which plays a critical role in neuronal cell survival; differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor; gp130 and leukemia inhibitory factor receptor; facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength; as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.
Synonyms -
Reference Data
Protein Families Druggable Genome
Protein Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.