DOK1 Rabbit Polyclonal Antibody
Anti-DOK1 (phospho-Tyr398) Rabbit Polyclonal Antibody
Product Datasheet for 'TA324072'
|Recommend Dilution||WB: 1:500-1000, IHC: 1:50-100|
|Reactivity||Human, Mouse, Rat|
|Immunogen||Peptide sequence around phosphorylation site of tyrosine 398 (E-G-Y(p)-E-L) derived from Human p62Dok.|
|Formulation||PBS pH7.3, 0.05% NaN3, 50% glycerol|
|Purification||Antigen affinity purification|
|Predicted Protein Size||62 kDa|
|Gene Name||docking protein 1|
|Background||DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.|
|Protein Families||Druggable Genome|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.