EGF Rabbit Polyclonal Antibody
Anti-EGF Rabbit Polyclonal Antibody
Product Datasheet for 'TA324064'
|Recommend Dilution||ELISA: 1:1000-5000, WB: 1:500-2000, IHC: 1:25-100|
|Reactivity||Human, Mouse, Rat|
|Immunogen||Fusion protein corresponding to a region derived from 926-1026 amino acids of human epidermal growth factor|
|Formulation||PBS pH7.3, 0.05% NaN3, 50% glycerol|
|Purification||Antigen affinity purification|
|Predicted Protein Size||134 kDa|
|Gene Name||epidermal growth factor|
|Background||This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth; proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor; epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants|
|Protein Families||Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transmembrane|
|Protein Pathways||Bladder cancer, Cytokine-cytokine receptor interaction, Endocytosis, Endometrial cancer, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, MAPK signaling pathway, Melanoma, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.