ACOX1 Rabbit Polyclonal Antibody
Anti-ACOX1 rabbit polyclonal antibody
Product Datasheet for 'TA324047'
|Recommend Dilution||ELISA: 1:1000-2000, WB: 1:200-1000, IHC: 1:15-50|
|Reactivity||Human, Mouse, Rat|
|Immunogen||Fusion protein corresponding to C terminal 250 amino acids of human acyl-CoA oxidase 1, palmitoyl|
|Formulation||PBS pH7.3, 0.05% NaN3, 50% glycerol|
|Purification||Antigen affinity purification|
|Predicted Protein Size||74 kDa|
|Gene Name||acyl-CoA oxidase 1, palmitoyl|
|Background||The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.|
|Synonyms||ACOX; PALMCOX; SCOX|
|Protein Families||Druggable Genome|
|Protein Pathways||alpha-Linolenic acid metabolism, Biosynthesis of unsaturated fatty acids, Fatty acid metabolism, Metabolic pathways, PPAR signaling pathway|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.