Myocilin (MYOC) Rabbit Polyclonal Antibody

USD 335.00


Availability*
In Stock

Size
    • 100 ul


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Specifications

Product Data
Applications WB
Recommend Dilution WB: 1:500-2000
Reactivity Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein corresponding to C terminal 260 amino acids of human myocilin, trabecular meshwork inducible glucocorticoid response
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration 2.55 mg/ml
Purification Antigen affinity purification
Predicted Protein Size 57 kDa
Gene Name myocilin
Background Myocilin (MYOC), also known as TIGR or GLC1A, is a secreted glycoprotein of the olfactomedin family, originally identified in trabecular meshwork cells after prolonged treatment with glucocorticoids, and, independently, in the retina. It may participate in the obstruction of fluid outflow in the trabecular meshwork. Defects in MYOC are the cause of primary open angle glaucoma (POAG). MYOC has a molecular weight of 55-57 kDa, besides, a 66-kDa form, which could be a result of post-translational modifications, has also been reported in some researches.
Synonyms GLC1A; GPOA; JOAG; JOAG1; TIGR
Reference Data
Protein Families Druggable Genome, Secreted Protein

Citations (1)

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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ANTIBODY VALIDATION 101
BOGO Free lysates
68 Mouse Clones