NMDAR2C (GRIN2C) Rabbit Polyclonal Antibody
Anti-GRIN2C Rabbit Polyclonal Antibody
Product Datasheet for 'TA323553'
|Recommend Dilution||ELISA: 1:2000-10000, IHC: 1:100-300|
|Reactivity||Human, Mouse, Rat|
|Immunogen||Synthetic peptide corresponding to a region derived from 1201-1215 amino acids of human glutamate receptor, ionotropic, N-methyl D-aspartate 2C|
|Formulation||PBS pH7.3, 0.05% NaN3, 50% glycerol|
|Purification||Antigen affinity purification|
|Gene Name||glutamate ionotropic receptor NMDA type subunit 2C|
|Background||N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation; an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A); NMDAR2B (GRIN2B); NMDAR2C (GRIN2C); and NMDAR2D (GRIN2D).|
|Synonyms||GluN2C; NMDAR2C; NR2C|
|Protein Families||Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane|
|Protein Pathways||Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Long-term potentiation, Neuroactive ligand-receptor interaction|
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