Laminin (LAMA1) Rabbit Polyclonal Antibody

CAT#: TA322580

Anti-LAMA1 Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human brain tissue using TA322580 (LAMA1 Antibody) at dilution 1/70 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA322580 (LAMA1 Antibody) at dilution 1/70, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA322580 (LAMA1 Antibody) at dilution 1/70 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA322580 (LAMA1 Antibody) at dilution 1/70, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human brain
  Predicted cell location: Cytoplasm
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 1606-1620 amino acids of Human laminin, alpha 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: laminin subunit alpha 1
• Database Link:
  NP_005550
  Entrez Gene 284217 Human
  UniProt ID P25391
• Background: Laminin subunit alpha-1?is a?protein?that in humans is encoded by the?LAMA1?gene. Laminin is a complex glycoprotein; consisting of three different polypeptide chains (alpha; beta; gamma); which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Alpha-1 is a subunit of laminin-1 (laminin-111 or EHS laminin) and laminin-3 (laminin-121 or S-laminin). Binding to cells via a high affinity receptor; laminin is thought to mediate the attachment; migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
• Synonyms: LAMA; PTBHS; S-LAM-alpha

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS
• Protein Pathways: ECM-receptor interaction, Focal adhesion, Pathways in cancer, Small cell lung cancer