PDCD10 Rabbit Polyclonal Antibody

CAT#: TA322434

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Anti-PDCD10 Rabbit Polyclonal Antibody


 Product Datasheet for 'TA322434'

USD 335.00


Availability*
2 Weeks

Size
    • 100 ul


Product images

Specifications

Product Data
Applications IHC, WB
Recommend Dilution ELISA: 1:1000-5000, WB: 1:200-1000, IHC: 1:25-100
Reactivity Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Full length fusion protein
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration 0.6mg/ml
Purification Antigen affinity purification
Predicted Protein Size 25 kDa
Gene Name programmed cell death 10
Background This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25; and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations; which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants; encoding the same protein; have been identified.
Synonyms CCM3; TFAR15
Reference Data
Protein Families Druggable Genome
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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