PDCD10 Rabbit Polyclonal Antibody
Anti-PDCD10 Rabbit Polyclonal Antibody
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | ELISA: 1:1000-5000, WB: 1:200-1000, IHC: 1:25-100 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Full length fusion protein |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 25 kDa |
Gene Name | programmed cell death 10 |
Database Link | |
Background | This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25; and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations; which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants; encoding the same protein; have been identified. |
Synonyms | CCM3; TFAR15 |
Reference Data | |
Protein Families | Druggable Genome |
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