PDCD10 Rabbit Polyclonal Antibody

CAT#: TA322434

Anti-PDCD10 Rabbit Polyclonal Antibody

Product images

Predicted band size: 25 kDa. Positive control: Hela, Jurkat and 231 cell lysate. Recommended dilution: 1/200-1000. (Gel: 12%SDS-PAGE Lane 1: Hela cell lysate Lane 2: Jurkat cell lysate Lane 3: 231 cell lysate Lysates: 50 ug per lane Primary antibody: 1/200dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 10 seconds)

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  Predicted cell location: Cytoplasm. Positive control: Human tonsil tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human tonsil tissue using PDCD10 antibody at dilution 1/20, on the right is treated with the fusion protein. (Original magnification: x200)

Specifications

Product Data

• Applications: IHC, WB
• Recommend Dilution: ELISA: 1:1000-5000, WB: 1:200-1000, IHC: 1:25-100
• Reactivity: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Full length fusion protein
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: 0.6mg/ml
• Purification: Antigen affinity purification
• Predicted Protein Size: 25 kDa
• Gene Name: programmed cell death 10
• Database Link:
  NP_009148
  Entrez Gene 56426 MouseEntrez Gene 494345 RatEntrez Gene 11235 Human
• Background: This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25; and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations; which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants; encoding the same protein; have been identified.
• Synonyms: CCM3; TFAR15

Reference Data

• Protein Families: Druggable Genome