Neurogenin 1 (NEUROG1) Rabbit Polyclonal Antibody

CAT#: TA321749

Anti-NEUROG1 Rabbit Polyclonal Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 40 μg Lane 1-5: Hela A375 HepG2 Mouse testis tissue 293T cell lysates Primary antibody: TA321749 (NEUROG1 Antibody) at dilution 1/250 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 1 minute

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA321749 (NEUROG1 Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA321749 (NEUROG1 Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Hela, A375, HepG2, Mouse testis tissue, 293T cell lysates
  IHC: 50-200
  Positive control: Human tonsil
  Predicted cell location: Nucleus
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 26-39 amino acids of Human neurogenin 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 26 kDa
• Gene Name: neurogenin 1
• Database Link:
  NP_006152
  Entrez Gene 18014 MouseEntrez Gene 4762 Human
  UniProt ID Q92886
• Background: Neurogenin-1?is a?protein?that in humans is encoded by the?NEUROG1?gene. Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis. NEUROG1 has been shown to interact with CREB-binding protein and decapentaplegic homolog 1.
• Synonyms: AKA; bHLHa6; Math4C; NEUROD3; ngn1

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors