FRA1(FOSL1) Rabbit Polyclonal Antibody
Anti-FOSL1 Rabbit Polyclonal Antibody
Product Datasheet for 'TA321715'
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|Recommend Dilution||ELISA: 1:1000-5000, WB: 1:500-2000|
|Reactivity||Human, Mouse, Rat|
|Immunogen||Synthetic peptide corresponding to a region derived from 2-16 amino acids of Human FOS-like antigen 1|
|Formulation||PBS pH7.3, 0.05% NaN3, 50% glycerol|
|Purification||Antigen affinity purification|
|Predicted Protein Size||29kDa|
|Gene Name||FOS like 1, AP-1 transcription factor subunit|
|Background||Fos-related antigen 1 is a protein that in humans is encoded by the FOSL1 gene. The Fos gene family consists of 4 members: FOS; FOSB; FOSL1; and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family; thereby forming the transcription factor complex AP-1. As such; the FOS proteins have been implicated as regulators of cell proliferation; differentiation; and transformation. FOSL1 has been shown to interact with USF1 (human gene) and C-jun.|
|Protein Families||Transcription Factors, Druggable Genome|
|Protein Pathways||Wnt signaling pathway|