Transglutaminase 2 (TGM2) Rabbit Polyclonal Antibody

CAT#: TA321660

Anti-TGM2 Rabbit Polyclonal Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 50 μg Lane 1-4: Lovo cells hela cells human liver cancer tissue Human fetal liver tissue Primary antibody: TA321660 (TGM2 Antibody) at dilution 1/150 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute

• 

  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA321660 (TGM2 Antibody) at dilution 1/15 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA321660 (TGM2 Antibody) at dilution 1/15, treated with fusion protein. (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA321660 (TGM2 Antibody) at dilution 1/15 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA321660 (TGM2 Antibody) at dilution 1/15, treated with fusion protein. (Original magnification: ×200)

Show all 5 images

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Lovo and hela cells, human liver cancer and fetal liver tissue
  IHC: 15-50
  Positive control: Human cervical cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to C terminal 250 amino acids of human transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 77 kDa
• Gene Name: transglutaminase 2
• Database Link:
  NP_004604
  Entrez Gene 21817 MouseEntrez Gene 7052 Human
  UniProt ID P21980
• Background: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved; they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer; is induced by retinoic acid; and appears to be involved in apoptosis. Finally; the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
• Synonyms: G-ALPHA-h; GNAH; HEL-S-45; TG2; TGC

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Huntington's disease