Alkyl DHAP synthase (AGPS) Rabbit Polyclonal Antibody
Anti-AGPS Rabbit Polyclonal Antibody
Product Datasheet for 'TA321590'
|Recommend Dilution||ELISA: 1:2000-5000, IHC: 1:25-100|
|Reactivity||Human, Mouse, Rat|
|Immunogen||Fusion protein corresponding to C terminal 300 amino acids of human alkylglycerone phosphate synthase|
|Formulation||PBS pH7.3, 0.05% NaN3, 50% glycerol|
|Purification||Antigen affinity purification|
|Gene Name||alkylglycerone phosphate synthase|
|Background||This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome.|
|Synonyms||ADAP-S; ADAS; ADHAPS; ADPS; ALDHPSY; RCDP3|
|Protein Pathways||Ether lipid metabolism, Metabolic pathways|
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