MMP15 Rabbit Polyclonal Antibody

CAT#: TA321486

Anti-MMP15 Rabbit Polyclonal Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-4: Mouse stomach tissue Mouse heart tissue Mouse liver tissue HT29 cells Primary antibody: TA321486 (MMP15 Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Mouse stomach, heart and liver tissue, HT-29 cells
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to C terminal 300 amino acids of human matrix metallopeptidase 15 (membrane-inserted)matrix metallopeptidase 15 (membrane-inserted)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 76 kDa
• Gene Name: matrix metallopeptidase 15
• Database Link:
  NP_002419
  Entrez Gene 17388 MouseEntrez Gene 4324 Human
  UniProt ID P51511
• Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes; such as embryonic development; reproduction; and tissue remodeling; as well as in disease processes; such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However; the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted.
• Synonyms: MT2-MMP; MTMMP2; SMCP-2

Reference Data

• Protein Families: Druggable Genome, Protease, Transmembrane