Ku70 (XRCC6) Rabbit Polyclonal Antibody

CAT#: TA321351

Anti-XRCC6 Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA321351 (XRCC6 Antibody) at dilution 1/10 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA321351 (XRCC6 Antibody) at dilution 1/10, treated with fusion protein. (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA321351 (XRCC6 Antibody) at dilution 1/10 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA321351 (XRCC6 Antibody) at dilution 1/10, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 10-50
  Positive control: Human colon cancer
  Predicted cell location: Nucleus
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a C terminal 300 amino acids of human X-ray repair complementing defective repair in Chinese hamster cells 6
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: X-ray repair complementing defective repair in Chinese hamster cells 6
• Database Link:
  NP_001460
  Entrez Gene 14375 MouseEntrez Gene 2547 Human
  UniProt ID P12956
• Background: The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair; transposition; and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
• Synonyms: CTC75; CTCBF; G22P1; KU70; ML8; TLAA

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Non-homologous end-joining