ITGB6 Rabbit Polyclonal Antibody

CAT#: TA321227

Anti-ITGB6 Rabbit Polyclonal Antibody


USD 380.00

4 Weeks*

Size
    • 100 ul

Product Images

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Specifications

Product Data
Applications IHC
Recommended Dilution IHC: 50-300
Positive control: Human esophagus cancer
Predicted cell location: Cytoplasm and Cell membrane
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein corresponding to a region derived from 139-434 amino acids of human integrin, beta 6
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name integrin subunit beta 6
Background Integrin beta-6 is a protein that in humans is encoded by the ITGB6 gene. Integrin; beta 6 has been shown to interact with FHL2. Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion.
Synonyms AI1H
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.