Adenosine A3 Receptor (ADORA3) Rabbit Polyclonal Antibody

CAT#: TA321175

Anti-ADORA3 Rabbit Polyclonal Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-2: LOVO cell Mouse liver tissue lysates Primary antibody: TA321175 (ADORA3 Antibody) at dilution 1/550 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 20 seconds

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  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA321175 (ADORA3 Antibody) at dilution 1/95. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: LOVO cell, Mouse liver tissue lysates
  IHC: 50-200
  Positive control: Human prostate cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to C terminal 66 amino acids of human Adenosine receptor A3
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 36 kDa
• Gene Name: adenosine A3 receptor
• Database Link:
  NP_000668
  Entrez Gene 11542 MouseEntrez Gene 140 Human
  UniProt ID P0DMS8
• Background: This gene encodes a protein that belongs to the family of adenosine receptors; which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia; it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury; it has been implicated in both neuroprotective and neurodegenerative effects; and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: A3AR

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction