CD8A Rat Monoclonal Antibody [Clone ID: 53-6.7]

CAT#: TA320299

Rat Anti-Mouse CD8a Purified (100 ug)


 Product Datasheet for 'TA320299'

  View other "53-6.7" antibodies (14)

USD 165.00


Availability*
5 Days

Size
    • 100 ug


Product images

Specifications

Product Data
Clone Name 53-6.7
Applications FC
Recommend Dilution Flow, IHC, IP
Reactivity Mouse
Host Rat
Clonality Monoclonal
Formulation Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5-1mg/ml (lot dependent)
Purification Affinity purified
Gene Name Mus musculus CD8 antigen, alpha chain (Cd8a), transcript variant 2
Background The 53-6.7 monoclonal antibody reacts with the mouse CD8a molecule. CD8a is an approximately 32-34 kDa cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha beta) or as a homodimer (CD8 alpha alpha). A majority of thymocytes and a subpopulation of mature alpha beta TCR T cells express CD8 alpha beta while gamma delta TCR T cells, a subpopulation of intestinal intraepithelial lymphocytes (IELs) and dendritic cells express CD8 alpha alpha. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells.
Synonyms BB154331; Ly-2; Ly-35; Ly-B; Lyt-2
Reference Data

Other Versions

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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