ZNF336 (GZF1) Rabbit Polyclonal Antibody

CAT#: TA320001

Rabbit Polyclonal GZF1 Antibody

Product Images

Western blot analysis of GZF1 in human heart tissue lysate with GZF1 antibody at 1 ug/mL.

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  Immunohistochemistry of GZF1 in human kidney tissue with GZF1 antibody at 2.5 ug/mL.

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  Immunofluorescence of GZF1 in human kidney tissue with GZF1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 2.5 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: GZF1 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human GZF1.
• Formulation: GZF1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: GZF1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: GDNF inducible zinc finger protein 1
• Database Link:
  NP_071927
  Entrez Gene 64412 Human
  UniProt ID Q9H116
• Background: GZF1 Antibody: The GDNF-inducible zinc finger protein 1 (GZF1) is a sequence-specific transcriptional repressor with a BTB/POZ domain and ten zinc finger motifs whose expression is required for renal branching morphogenesis during kidney development. GZF1 binds to the 5'regulatory region of the homeodomain protein HOXA10, suggesting that GZF1 may play a role in morphogenesis other than kidney development. Recent experiments have indicated that GZF1 associates with nucleolin and this association is mediated by the first four zinc finger motifs of GZF1. It is thought that Nucleolin modulates the subcellular localization of GZF1 as well as its transcriptional repressor activity.
• Synonyms: ZBTB23; ZNF336

Reference Data

• Protein Families: Transcription Factors