Zinc finger MIZ domain containing protein 1 (ZMIZ1) Rabbit Polyclonal Antibody
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USD 200.00
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Specifications
Product Data | |
Applications | IF, WB |
Recommended Dilution | WB: 0.5 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | ZIMP10 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human ZIMP10. |
Formulation | ZIMP10 Antibody is supplied in PBS containing 0.02% sodium azide. |
Concentration | 1ug/ul |
Purification | ZIMP10 Antibody is affinity chromatography purified via peptide column. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | zinc finger MIZ-type containing 1 |
Database Link | |
Background | ZIMP10 Antibody: ZIMP10, also known as ZMIZ1, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein initially identified as a transcriptional co-activator of the androgen receptor (AR). ZIMP10 and the related protein ZIMP7 interact with PIAS3 and enhances AR-mediated transcription. Later experiments showed that ZIMP10 is also a co-activator of the p53 tumor suppressor. Mice deficient in ZIMP10 result in embryonic lethality by E10.5; these embryos reveal severe defects in the reorganization of the yolk sac vascular plexus, indicating that ZIMP10 plays an important role in proper vascular development. |
Synonyms | hZIMP10; MIZ; RAI17; TRAFIP10; ZIMP10 |
Reference Data |
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