SIK3 Chicken Polyclonal Antibody

CAT#: TA319854

Chicken Polyclonal SIK3 Antibody

Product Images

Western blot analysis of SIK3 in rat brain tissue lysate with SIK3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

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  Immunofluorescence of SIK3 in rat brain cells with SIK3 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Chicken
• Isotype: IgY
• Clonality: Polyclonal
• Immunogen: SIK3 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SIK3.
• Formulation: SIK3 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: SIK3 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: SIK family kinase 3
• Database Link:
  NP_079440
  Entrez Gene 70661 MouseEntrez Gene 684112 RatEntrez Gene 23387 Human
  UniProt ID Q9Y2K2
• Background: SIK3 Antibody: Salt-inducible kinase family (SIKs) proteins are thought to have a role in steroidogenesis, adipogenesis or regulation of tumor malignancy. Three members (SIK1, SIK2 and SIK3) in the SIK family have been identified thus far. Their kinase domain sequences are closely homologous to those of AMP-activated protein kinase (AMPK). SIK3 can be phosphorylated by a tumor-suppressor kinase LKB1. It is highly and preferentially expressed in ovarian tumors but not in adenomyosis and leiomyoma and may be a potential diagnostic marker for ovarian cancers.
• Synonyms: L19; QSK; SIK-3

Reference Data

• Protein Families: Druggable Genome, Protein Kinase