CD168 (HMMR) Rabbit Polyclonal Antibody

CAT#: TA319659

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Rabbit Polyclonal RHAMM Antibody



USD 484.00


Availability*
2 Weeks

Size
    • 100 ug


Product images

Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution WB: 1 ug/mL, ICC: 2.5 ug/mL, IF: 5 ug/mL
Reactivity Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen RHAMM antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of human RHAMM.
Formulation RHAMM Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification RHAMM Antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name hyaluronan mediated motility receptor
Background RHAMM Antibody: The hyaluronan-mediated motility receptor, also known as RHAMM, was initially identified as a soluble protein that could be released by sub-confluent migrating cells, promoting cell motility and invasion via interactions with hyaluronan (HA) and the cell surface. While RHAMM is normally poorly expressed in most normal tissues and is not required for embryonic development or normal cell homeostasis functions, its expression is increased during wound repair in response to hypoxia and fibrogenic factors. However, its overexpression is transforming in multiple types of cancers and is required for maintaining RAS transformation. RHAMM associates with BRCA1 and BARD1, attenuating the mitotic-spindle-promoting activity of RHAMM, which may contribute to tumor progression by promoting genomic instability.
Synonyms CD168; IHABP; RHAMM
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways ECM-receptor interaction
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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