CD48 Rabbit Polyclonal Antibody
Rabbit Polyclonal SLAMF2 Antibody
Product Datasheet for 'TA319627'
|Recommend Dilution||WB: 1 - 2 ug/mL|
|Reactivity||Human, Mouse, Rat|
|Immunogen||SLAMF2 antibody was raised against a 19 amino acid synthetic peptide near the center of human SLAMF2.|
|Formulation||SLAMF2 Antibody is supplied in PBS containing 0.02% sodium azide.|
|Purification||SLAMF2 Antibody is affinity chromatography purified via peptide column.|
|Gene Name||CD48 molecule|
|Background||SLAMF2 Antibody: The signaling lymphocyte-activation molecule family member 2 (SLAMF2), also known as CD48, is a GPI-anchored protein that exists as both a soluble and membrane-associated form and is expressed in almost all leukocyte populations particularly in mitogen-stimulated human lymphocytes. SLAMF2 is a high-affinity ligand for SLAMF4, also known as 2B4, as well as a low-affinity ligand for CD2, and can thus can stimulate cells expressing these receptors. It has been shown to be an IL-3-induced activating receptor on eosinophils and is likely to be involved in promoting allergic inflammation. SLAMF2 is also thought to be involved in the IL-18/IL-18R signaling cascade in T and natural killer cells to produce interferon-gamma.|
|Protein Families||Transmembrane, Druggable Genome|
|Protein Pathways||Natural killer cell mediated cytotoxicity|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.