Il17a Rat Monoclonal Antibody [Clone ID: 20B4.G10.F5]

CAT#: TA319587

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Rat monoclonal Mouse IL-17A antibody

Product Datasheet for 'TA319587'

USD 530.00

In Stock

    • 100 ug

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Product Data
Clone Name 20B4.G10.F5
Applications FC, WB
Recommended Dilution ELISA: 1:10,000, WB: 1:1000
Reactivity Mouse
Host Rat
Clonality Monoclonal
Immunogen This Protein A purified monoclonal antibody was produced in rats by repeated immunizations with full length recombinant mouse IL-17A protein (produced in E.coli) followed by hybridoma development.
Formulation 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Concentration 2.94mg/ml
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name interleukin 17A
Synonyms CTLA-8; CTLA8; IL-17; IL-17A; IL17
Note Mouse Interleukin-17A (IL-17A), also known as CTLA-8, is a proinflammatory cytokine member of a six-species family of proteins (IL-17A-17F). Mouse IL-17A protein is a homodimer consisting of two 134 amino acids peptides. IL-17A is secreted mainly by activated CD4+ and CD8+ T lymphocytes and acts through its receptor, IL-17R, to induce the expression of many mediators of inflammation, most strikingly, those that are involved in the proliferation, maturation and chemotaxis of neutrophils. Elevated levels of IL-17A have been associated with several conditions, including rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer and multiple sclerosis. There is 58% identity between the amino acid sequence of human and mouse IL-17A. Anti-IL-17A antibody is ideal for investigators involved in Immunology research.
Reference Data
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