IP10 (Cxcl10) Rabbit Polyclonal Antibody
Rabbit polyclonal anti-IP-10 antibody
Product Datasheet for 'TA319044'
|Recommend Dilution||WB: 0.5-4 ug/ml|
|Immunogen||E. coli-expressed recombinant rat IP-10|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Gene Name||C-X-C motif chemokine ligand 10|
|Background||IP-10 (interferon-gamma induced protein 10 kDa; in mouse also called cytokine responsive gene 2, Crg-2, or mob-1) is a highly inducible, primary response gene that belongs to the CXC chemokine superfamily. It was first cloned in 1985. Like Mig, IP-10 has no activity on neutrophils. Its functions include stimulation of monocytes, natural killer and T-cell migration, regulation of T-cell and bone marrow progenitor maturation, modulation of adhesion molecule expression as well as inhibition of angiogenesis. Mig and IP-10 share the same receptor, CXCR3.|
|Synonyms||C7; crg-2; gIP-10; IFI10; INP10; IP-10; mob-1; SCYB10|
|Protein Families||Druggable Genome, Secreted Protein, Transmembrane|
|Protein Pathways||Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.