PBR(TSPO) Rabbit Polyclonal Antibody

CAT#: TA318861

Rabbit polyclonal anti-TSPO/PBR (Peripheral-type Benzodiazepine Receptor) antibody

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 Product Datasheet for 'TA318861'

USD 400.00

In Stock

    • 100 ug

Product images


Product Data
Applications WB
Recommend Dilution WB: 0.5-4ug/ml, IHC: 10-20ug/ml
Reactivity Human, mouse, rat
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide surrounding amino acid 81 of mouse PBR
Isotype Rabbit IgG
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti-PBR polyclonal antibody in phosphate buffered saline (PBS), pH 7.2.
Reconstitution Method Reconstitute with PBS (pH7.3). To use this carrier-free antibody for conjugation experiment, we strongly recommend you to perform another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Concentration 0.2 mg/ml
Purification Affinity purified
Gene Name translocator protein
Background PBR (Peripheral-type Benzodiazepine Receptor) is a ubiquitous protein (18 kDa) found in most steroidogenic tissues. It is located primarily in the outer mitochondrial membrane of steroid-producing tissues and is found in association with a 34 kDa voltage-dependent anion channel protein (VDAC). PBR is involved in the regulation of cholesterol transport from the outer to the inner mitochondrial membrane. It is thought to be part of the mitochondrial permeability transition pore (PT) and to be involved in apoptosis.
Reference Data
Protein Families Transmembrane, Druggable Genome
Protein Pathways Neuroactive ligand-receptor interaction
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.