IL2 Receptor alpha(IL2RA) Rabbit Monoclonal Antibody [Clone ID: EPR6452]

CAT#: TA310265

Rabbit Monoclonal antibody against CD25

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 Product Datasheet for 'TA310265'

USD 515.00


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Size
    • 100 ul

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Specifications

Product Data
Clone Name EPR6452
Applications IHC
Recommend Dilution IHC-P 1:250 - 1:500; ICC 1:100-1:250
Reactivity Human (Does not react with: Mouse, Rat)
Host Rabbit
Clonality Monoclonal
Immunogen A recombinant protein fragment corresponding to human CD25 was used as an immunogen.
Isotype IgG
Formulation pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Reconstitution Method Reconstitute with PBS (pH7.3). To use this carrier-free antibody for conjugation experiment, we strongly recommend you to perform another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Tissue culture supernatant
Gene Name interleukin 2 receptor subunit alpha
Background CD25, or interleukin 2 (IL2) receptor alpha (IL2RA), and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (CD25) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble CD25 has been isolated and determined to result from extracellular proteolyisis. Mutations in CD25 are associated with interleukin 2 receptor alpha deficiency (1).
Synonyms CD25|IDDM10|IL2R|IMD41|TCGFR|p55
Note Does not react with Mouse, Rat; Is unsuitable for IP
Reference Data
Protein Families ES Cell Differentiation/IPS, Transmembrane, Druggable Genome
Protein Pathways Cytokine-cytokine receptor interaction, Endocytosis, Jak-STAT signaling pathway, Hematopoietic cell lineage
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.