PTEN Rabbit Polyclonal Antibody

CAT#: TA309963

Rabbit anti-PTEN (Phospho-Ser380/Thr382/Thr383) polyclonal antibody (Phospho-specific)

Product Images

Western blot analysis of extracts from HT29 cells untreated or treated with calyculin A, using PTEN (phospho-Ser380/Thr382/Thr383) antibody.

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  Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using PTEN (phospho-Ser380/Thr382/Thr383) antibody.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:500~1:1000, IHC: 1:50~1:100
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from humanPTEN around the phosphorylation site of serine 380 and threonine 382/383(R-Y-SP-D-TP-TP-D-S).
• Formulation: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: phosphatase and tensin homolog
• Database Link:
  NP_000305
  Entrez Gene 19211 MouseEntrez Gene 50557 RatEntrez Gene 5728 Human
  UniProt ID P60484
• Synonyms: 10q23del; BZS; CWS1; DEC; GLM2; MHAM; MMAC1; PTEN1; TEP1

Reference Data

• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: Endometrial cancer, Focal adhesion, Glioma, Inositol phosphate metabolism, Melanoma, p53 signaling pathway, Pathways in cancer, Phosphatidylinositol signaling system, Prostate cancer, Small cell lung cancer, Tight junction